"KAT7" Related Products


Recombinant Human K(Lysine) Acetyltransferase 7, GST-tagged

Cat. No.: KAT7-1601H
Product Overview: Recombinant full-length human KAT7 (MYST2) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: KAT7 or K (lysine) acetyltransferase 5 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein which play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and non-histone proteins. KAT7 acts as a transcriptional inhibitor and inhibited AR-mediated transactivation of reporter constructs in CV-1 and PC-3 cells. KAT7 is part of a multisubunit complex that can acetylate histones H3 and H4.
Applications: Western Blot
Molecular Weight: 110 kDa
Expression System: Sf9 insect cells using baculovirus.
Species: Human
Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 25% glycerol.
Purity: > 85 %
Concentration: 0.1 ug/ul
Sequences: Full-length
Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways: Androgen Receptor Signaling Pathway; Regulation of Androgen receptor activity
Gene Name: KAT7 K(lysine) acetyltransferase 7 [ Homo sapiens ]
Official Symbol: KAT7
Synonyms: KAT7; HBO1; HBOA; MYST2; MYST histone acetyltransferase 2; Histone acetyltransferase binding to ORC1; MYST-2; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; OTTHUMP00000220716; OTTHUMP00000220718; histone acetyltransferase MYST2; EC2.3.1.48
Gene ID: 11143
mRNA Refseq: NM_007067
Protein Refseq: NP_008998
MIM: 609880
UniProt ID: O95251
Chromosome Location: 17q21.32
Function: histone acetyltransferase activity; metal ion binding; protein binding; sequence-specific DNA binding transcription factor activity; transferase activity, transferring acyl groups other than aminoacyl groups; zinc ion binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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