"RAC1" Related Products

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Recombinant Human Ras-Related C3 Botulinum Toxin Substrate 1 (rho family, small GTP binding protein Rac1), GST-tagged

Cat. No.: RAC1-1625H
Product Overview: Recombinant full-length human RAC1 was expressed in E. coli cells using an N-terminal GST tag.
Description: RAC1 is a member of the Rho family and is a GTPase that is part of the small GTP-binding protein superfamily. RAC1 is involved in a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Role of RAC1 in colorectal cancer has been reported after analysis of the protein expression level and activities of this protein in matched sets of tumor and non-tumor tissues.
Applications: Kinase Assay; Western Blot
Molecular Weight: 47 kDa
Expression System: E. coli
Species: Human
Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.
Purity: > 95 %
Concentration: 0.2 ug/ul
Sequences: Full-length
Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways: Adherens junction; Amyotrophic lateral sclerosis (ALS); Axon guidance; B cell receptor signaling pathway; Chemokine signaling pathway; Colorectal cancer; Epithelial cell signaling in Helicobacter pylori infection; Fc epsilon RI signaling pathway; Fc gamma R-mediated phagocytosis; Focal adhesion; Leukocyte transendothelial migration; MAPK signaling pathway; Natural killer cell mediated cytotoxicity; Neurotrophin signaling pathway; Pancreatic cancer
Gene Name: RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) [ Homo sapiens ]
Official Symbol: RAC1
Synonyms: RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); MIG5; Rac-1; TC-25; p21-Rac1; MGC111543; ras-related C3 botulinum toxin substrate 1; OTTHUMP00000151196; OTTHUMP00000151197; ras-like protein TC25; cell migration-inducing gene 5 protein; Ras-related C3 botulinum toxin substrate 1; Cell migration-inducing gene 5 protein; Ras-like protein TC25
Gene ID: 5879
mRNA Refseq: NM_006908
Protein Refseq: NP_008839
MIM: 602048
UniProt ID: P63000
Chromosome Location: 7p22
Function: GTP binding; GTP-dependent protein binding; GTPase activity; enzyme binding; nucleotide binding; protein binding; thioesterase binding

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