"YWHAQ" Related Products


Recombinant Human Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Theta Polypeptide, GST-tagged

Cat. No.: YWHAQ-4899H
Product Overview: Recombinant full-length human YWHAQ was expressed in E. coli cells using an N-terminal GST tag.
Description: YWHAQ (also known as tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein, theta polypeptide) is a member of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. Through interaction with ASK1, c-jun NH-terminal kinase, and p38 mitogen-activated protein kinase (MAPK), YWHAQ plays an important role in controlling apotopsis. Induced expression of YWHAQ protein has been reported in patients with amyotrophic lateral sclerosis. Additionally, YWHAQ has been observed to mediate nucleocytoplasmic shuttling of the N protein (coronavirus nucleocapsid protein) which causes severe acute respiratory syndrome.
Applications: Western Blot
Molecular Weight: 56kDa
Expression System: E.coli
Species: Human
Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl,10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity: >95 %
Concentration: 0.2ug/ul
Sequences: Full-length
Storage: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways: Cell cycle; Pathogenic Escherichia coli infection – EHEC; Pathogenic Escherichia coli infection - EPEC; Alpha6-Beta4 Integrin Signaling Pathway; Calcium Regulation in the Cardiac Cell; Class I PI3K signaling events mediated by Akt; ErbB1 downstream signaling; FoxO family signaling; IL-3 Signaling Pathway; Insulin-mediated glucose transport; LKB1 signaling events; Myometrial Relaxation and Contraction Pathways; Neurotrophin signaling pathway; Oocyte meiosis; Pathogenic Escherichia coli infection
Gene Name: YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide[ Homo sapiens ]
Official Symbol: YWHAQ
Synonyms: YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; 14-3-3 theta; 14-3-3 tau; 14-3-3 T-cell; HS1; 1C5;14-3-3; tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide protein tau; 14-3-3 protein tau; OTTHUMP00000015730; 14-3-3 protein theta; 14-3-3 protein T-cell; Protein HS1; tyrosine 3/tryptophan 5 -monooxygenase activation protein,theta polypeptide
Gene ID: 10971
mRNA Refseq: NM_006826
Protein Refseq: NP_006817
MIM: 609009
UniProt ID: P27348
Chromosome Location: 2p25.1
Function: protein N-terminus binding; protein domain specific binding; protein binding

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