"Ctf1" Related Products

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Recombinant Mouse Cardiotrophin 1

Cat. No.: Ctf1-342M
Product Overview: Recombinant Mouse Ctf1 was expressed in E.coli and purified by using conventional chromatography techniques.
Description: CT-1 is a member of the IL6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL11, IL6 and possibly NNT-1/ BCSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations.
Source: Mouse
Host: E.coli
Form: Supplied as a lyophilized powder.
Purity: >98% pure by SDS PAGE and HPLC
Sequence: Region of Cardiotrophin 1 protein corresponding to amino acids SQREGSLEDH QTDSSISFLP HLEAKIRQTH NLARLLTKYA EQLLEEYVQQ QGEPFGLPGF SPPRLPLAGL SGPAPSHAGL PVSERLRQDA AALSVLPALL DAVRRRQAEL NPRAPRLLRS LEDAARQVRA LGAAVETVLA ALGAAARGPG PEPVTVATLF TANSTAGIFS AKVLG
Molecular Mass: 21.3 kDa
Applications: Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions
Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Bioactivity: The ED50 as determined by the dose-dependent proliferation of TF-1 cells was <1.0 ng/ml, corresponding to a specific activity of >1 x 10^6units/mg.
Storage: Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene Name: Ctf1 cardiotrophin 1 [ Mus musculus ]
Official Symbol: Ctf1
Synonyms: Ctf1; CT-1; cardiotrophin-1
Gene ID: 13019
mRNA Refseq: NM_007795
Protein Refseq: NP_031821
UniProt ID: Q60753
Chromosome Location: 7; 7 F3
Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; MicroRNAs in cardiomyocyte hypertrophy
Function: cytokine activity; leukemia inhibitory factor receptor binding

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