Recombinant Human Hypoxanthine Phosphoribosyltransferase 1, His-tagged
Cat.No. : | HPRT1-1796H |
Product Overview : | Recombinant human HPRT1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | HPRT1-1796H |
Description : | Hypoxanthine-guanine phosphoribosyltransferase, also known as HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. The enzyme primarily functions to salvage purines from degraded DNA to renewed purine synthesis. In this role, it acts as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP. |
Concentration : | 0.5 mg/ml |
Source : | Human |
Host : | E.coli |
Form : | Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol. |
Purity : | > 95% by SDS - PAGE |
Sequence : | 1-218 amino acids: MGSSHHHHHH SSGLVPRGSH MATRSPGVVI SDDEPGYDLD LFCIPNHYAE DLERVFIPHG LIMDRTERLA RDVMKEMGGH HIVALCVLKG GYKFFADLLD YIKALNRNSD RSIPMTVDFI RLKSYCNDQS TGDIKVIGGD DLSTLTGKNV LIVEDIIDTG KTMQTLLSLV RQYNPKMVKV ASLLVKRTPR SVGYKPDFVG FEIPDKFVVG YALD |
Molecular Mass : | 26.7 kDa (238aa), confirmed by MALDI-TOF |
Applications : | SDS-PAGE |
Storage : | Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Gene Name : | HPRT1 hypoxanthine phosphoribosyltransferase 1 [ Homo sapiens ] |
Official Symbol : | HPRT1 |
Synonyms : | HPRT1; hypoxanthine phosphoribosyltransferase 1; HPRT; HGPRT; hypoxanthine-guanine phosphoribosyltransferase; HGPRTase; EC 2.4.2.8; Lesch-Nyhan syndrome |
Gene ID : | 3251 |
mRNA Refseq : | NM_000194 |
Protein Refseq : | NP_000185 |
MIM : | 308000 |
UniProt ID : | P00492 |
Chromosome Location : | Xq26.1 |
Pathway : | Drug metabolism - other enzymes; Metabolic pathways; Purine metabolism |
Function : | hypoxanthine phosphoribosyltransferase activity; magnesium ion binding; protein binding; protein homodimerization activity; transferase activity, transferring glycosyl groups |
Products Types
◆ Recombinant Protein | ||
HPRT1-341C | Recombinant Cynomolgus Monkey HPRT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HPRT1-2696M | Recombinant Mouse HPRT1 Protein, GST-tagged | +Inquiry |
HPRT1-2560R | Recombinant Rat HPRT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HPRT1-0321H | Recombinant Human HPRT1 Protein (M1-A218), Tag Free | +Inquiry |
HPRT1-1096H | Recombinant Human HPRT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
HPRT1-5398HCL | Recombinant Human HPRT1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket