Native Human ApoLipoprotein CIII

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Native Human ApoLipoprotein CIII

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Cat.No. : APOC3-8040H
Product Overview : Human Apo-CIII is purified from delipidated VLDL(very low density lipoprotein). Impurities removed by affinity chromotography.
Description : Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.
Source : Human Plasma
Species : Human
Form : 75 mM PBS, 0.5 mM EDTA, pH 7.2
Molecular Mass : 8.75 kDa
Purity : >99% by SDS-PAGE
Storage : -20 °C Avoid repeat freezing and thawing
Gene Name : APOC3 apolipoprotein C-III [ Homo sapiens ]
Official Symbol : APOC3
Synonyms : APOC3; apolipoprotein C-III; apo-CIII; apoC-III; apolipoprotein C3; HALP2; APOCIII; MGC150353;
Gene ID : 345
mRNA Refseq : NM_000040
Protein Refseq : NP_000031
MIM : 107720
UniProt ID : P02656
Chromosome Location : 11q23-qter
Pathway : Chylomicron-mediated lipid transport, organism-specific biosystem; HDL-mediated lipid transport, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPAR signaling pathway, organism-specific biosystem;
Function : cholesterol binding; enzyme regulator activity; high-density lipoprotein particle receptor binding; lipase inhibitor activity; phospholipid binding;

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