Native Human PLAU

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Native Human PLAU

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Cat.No. : PLAU-8456H
Product Overview : LPA was purified from Human urine.
Description : Urokinase (UK) is a serine protease, which is one of biological plasminogen activators. It is involved in a number of biological functions including fibrinolysis, embryogenesis, cell migration, tissue remodeling, ovulation, and wound healing. It can be obtained from human urine or kidney cell culture. UK is a two-chain glycoprotein containing 411 amino acids with 12 dissulfide bonds. Its molecular weight is 54,000.
Source : Human
Species : Human
Form : Lyophilized powder
Bio-activity : 1 nM UK will cause a change in absorbance of 0.001 at 405 nm in 1 minute at R/T in 100 μl reaction mixture containing 0.05 M Tris-HCl, 0.1 M NaCl, pH 7.4, using S2444 (0.6mM) as the substrate.
Molecular Mass : 54.0 kDa
Purity : ≥0% by SDS - PAGE; ≥0% by HPLC
Storage : -20°C
Reconstitution : Reconstitute in sterile H2O to a concentration >100 ug/ml. The solution can then be diluted into other aqueous solutions.
Shipping : Gel pack
Gene Name : PLAU plasminogen activator, urokinase [ Homo sapiens ]
Official Symbol : PLAU
Synonyms : PLAU; plasminogen activator, urokinase; urokinase-type plasminogen activator; UPA; URK; U-plasminogen activator; plasminogen activator, urinary; ATF; QPD; u-PA; BDPLT5;
Gene ID : 5328
mRNA Refseq : NM_001145031
Protein Refseq : NP_001138503
MIM : 191840
UniProt ID : P00749
Chromosome Location : 10q24
Pathway : ATF-2 transcription factor network, organism-specific biosystem; Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; DNA damage response (only ATM dependent), organism-specific biosystem; Dissolution of Fibrin Clot, organism-specific biosystem;
Function : peptidase activity; protein binding; serine-type endopeptidase activity;

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