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Active Recombinant Human IFNG protein(Met1-Gln166)

Cat.No. : IFNG-8549H
Product Overview : Recombinant Human IFNG protein(NP_000610.2)(Met1-Gln166) was expressed in CHO.
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  • Gene Information
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similar : IFNG
Alias : IFNG; interferon, gamma; interferon gamma; IFN-gamma; immune interferon; IFG; IFI;
Source : CHO
Species : Human
Conjugate : N/A
Tag : N/A
Protein length : Met1-Gln166
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bioactivity : Measured in antiviral assays using WISH cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is 0.02-0.2 ng/mL.
MolecularMass : The secreted recombinant human γ-IFN consists of 143 amino acids and has a predicted molecular mass of 16.7 kDa. γ-IFN migrates as two bands with apparent molecular mass of 21&25 kDa probably due to different glycosylation.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 92 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
GeneName : IFNG interferon, gamma [ Homo sapiens ]
GeneNameWeblink : 3458
OfficialSymbol : IFNG
OfficialSymbolWeblink : 3458
GeneID : 3458
GeneIDWeblink : 3458
mRNARefseq : NM_000619
mRNARefseqWeblink : NM_000619.2
ProteinRefseqWeblink : NP_000610.2
MIMWeblink : 147570
UniProtID : P01579
UniProtIDWeblink : P01579
Synonyms : IFNG; interferon, gamma; interferon gamma; IFN-gamma; immune interferon; IFG; IFI;
MIM : 147570
Synonyms : IFNG; interferon, gamma; interferon gamma; IFN-gamma; immune interferon; IFG; IFI;
MIM : 147570

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the role of IFNG in tumor immunotherapy? 09/23/2022

IFNG plays an important role in tumor immunotherapy, which can activate the immune response of tumor cells, promote apoptosis of tumor cells and inhibit the proliferation of tumor cells.

What is the current progress in drug development for IFNG? 12/19/2021

The development of drugs for IFNG is currently in clinical trials, including monoclonal antibodies against IFNG receptors and inhibitors against IFNG signaling pathways.

How is IFNG related to muscle wasting? 12/02/2021

Studies have shown that IFNG can inhibit the occurrence of muscle atrophy, but the specific mechanism is not clear.

How can IFNG be used as a biomarker in clinical practice? 03/01/2021

In clinical practice, the expression level of IFNG can be measured to predict the progression and prognosis of the disease, and to guide the choice of treatment regimen.

Are there other coding variants in the IFNG gene? 07/12/2020

Yes, there are other coding variants in the IFNG gene that may have different functions and expression patterns.

Is the expression of IFNG affected by environmental factors? 05/26/2020

Such as nutritional status, inflammation levels, etc. Yes, the expression of IFNG is affected by environmental factors, such as nutritional status, inflammation level, etc.

Customer Reviews (3)

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Reviews
12/17/2022

    It is analyzed by X-ray crystallography or other crystallization techniques and has good crystallization properties.

    06/10/2022

      Easy to attach to the surface of cells or materials.

      04/02/2022

        IFNG products have a complete range of specifications for experimental designs of different sizes and needs.

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