Recombinant Human SAE1, His-GST tagged SAE1-8623H

Cat.No.:	SAE1-8623H
Product Overview:	Recombinant Human SAE1 (Q9UBE0) (Met1-Lys346), fused with the N-terminal polyhistidine-tagged GST tag, was produced in Baculovirus-Insect cells.
Source:	Baculovirus-Insect Cells
Species:	Human
Tag:	His-GST
Form:	Lyophilized from a 0.2μm filtered solution of 20mM Tris, 500mM NaCl, pH 7.4, 10% gly
Molecular Mass:	The recombinant human SAE1 /GST chimera consists of 583 amino acids and has a calculated molecular mass of 66.3 kDa. The recombinant protein migrates as an approximately 61 kDa band in SDS-PAGE under reducing conditions.
Endotoxin:	< 1.0 EU per μg of the protein as determined by the LAL method.
Stability:	Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage:	Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:	It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4ºC before opening to recover the entire contents.

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Gene Name:	SAE1 SUMO1 activating enzyme subunit 1 [ Homo sapiens ]
Official Symbol:	SAE1
Synonyms:	SAE1; SUMO1 activating enzyme subunit 1; SUMO-activating enzyme subunit 1; activator Of sumo 1; AOS1; FLJ3091; Sua1; activator of SUMO1; SUMO-1 activating enzyme subunit 1; sentrin/SUMO-activating protein AOS1; SUMO-1 activating enzyme E1 N subunit; ubiquitin-like 1-activating enzyme E1A; ubiquitin-like protein SUMO-1 activating enzyme; SUA1; UBLE1A; HSPC140;
Gene ID:	10055
mRNA Refseq:	NM_001145713
Protein Refseq:	NP_001139185
MIM:	613294
UniProt ID:	Q9UBE0
Chromosome Location:	19q13.32
Pathway:	Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem;
Function:	ATP-dependent protein binding; contributes_to SUMO activating enzyme activity; enzyme activator activity; ligase activity; nucleotide binding; protein C-terminus binding; protein binding; protein heterodimerization activity; protein heterodimerization activity; ubiquitin activating enzyme activity;