Native Human CRP

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Native Human CRP

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Cat.No. : CRP-8374H
Product Overview : Native Human CRP was purified from Plasma.
Description : C Reactive Protein is an acute phase protein with a molecular mass of approximately 114kDa. It is synthesised in the liver and is most commonly used as a marker for inflamation. Elevated CRP levels are seen in patients with coronary artery disease; hence it is also used in cardiology diagnostic tests to predict and monitor this disease.
Source : Plasma
Species : Human
Form : Liquid in 20mM TRIS buffer pH 8.0 containing 0.28M NaCl, 0.09% NaN3 and 5mM CaCl2.
Molecular Mass : 114kDa
Purity : Nominally greater than 99% of the protein is C-Reactive protein.
Gene Name : CRP C-reactive protein, pentraxin-related [ Homo sapiens ]
Official Symbol : CRP
Synonyms : CRP; C-reactive protein, pentraxin-related; C-reactive protein; pentraxin 1; PTX1; MGC88244; MGC149895;
Gene ID : 1401
mRNA Refseq : NM_000567
Protein Refseq : NP_000558
MIM : 123260
UniProt ID : P02741
Chromosome Location : 1q21-q23
Pathway : Classical antibody-mediated complement activation, organism-specific biosystem; Complement cascade, organism-specific biosystem; Creation of C4 and C2 activators, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Initial triggering of complement, organism-specific biosystem; Innate Immune System, organism-specific biosystem;
Function : Gram-positive bacterial cell surface binding; binding; cholesterol binding; choline binding; low-density lipoprotein particle binding; metal ion binding; protein binding; protein homodimerization activity;

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