Native Human CRP

• Cat.No.: CRP-8374H
• Product Overview: Native Human CRP was purified from Plasma.

Specification

• Description: C Reactive Protein is an acute phase protein with a molecular mass of approximately 114kDa. It is synthesised in the liver and is most commonly used as a marker for inflamation. Elevated CRP levels are seen in patients with coronary artery disease; hence it is also used in cardiology diagnostic tests to predict and monitor this disease.
• Source: Plasma
• Species: Human
• Form: Liquid in 20mM TRIS buffer pH 8.0 containing 0.28M NaCl, 0.09% NaN3 and 5mM CaCl2.
• Molecular Mass: 114kDa
• Purity: Nominally greater than 99% of the protein is C-Reactive protein.

Gene Information

• Gene Name: CRP C-reactive protein, pentraxin-related [ Homo sapiens ]
• Official Symbol: CRP
• Synonyms: CRP; C-reactive protein, pentraxin-related; C-reactive protein; pentraxin 1; PTX1; MGC88244; MGC149895
• Gene ID: 1401
• mRNA Refseq: NM_000567
• Protein Refseq: NP_000558
• MIM: 123260
• UniProt ID: P02741
• Chromosome Location: 1q21-q23
• Pathway: Classical antibody-mediated complement activation, organism-specific biosystem; Complement cascade, organism-specific biosystem; Creation of C4 and C2 activators, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Initial triggering of complement, organism-specific biosystem; Innate Immune System, organism-specific biosystem
• Function: Gram-positive bacterial cell surface binding; binding; cholesterol binding; choline binding; low-density lipoprotein particle binding; metal ion binding; protein binding; protein homodimerization activity