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Native Human GPX1

Cat.No. : GPX1-8429H
Product Overview : Native Human GPX1 was purified from Erythrocytes.
  • Specification
  • Gene Information
  • Related Products
Description : Peroxides in the cell can form highly reactive and damaging free radicals. Glutathione peroxidase (GPO) is a selenoenzyme with peroxidase activity, whose main biological purpose is the elimination of reactive oxygen species to protect the cell.
Source : Erythrocytes
Species : Human
Form : Frozen in 4.3mM sodium phosphate buffer, pH 7.0, containing 0.2mM DTT and sucrose at 0.25 mg/ml.
Unit Definition : One unit will catalyse oxidation by Hydrogen Peroxide of 1.0 micromole of reduced glutathione to oxidised glutathione per minute at pH 7.0 at 25°C.
Concentration : >30 U/mg
Reconstitution : Use of a 0.1M sodium acetate buffer pH 4.5 is recommended.
Gene Name : GPX1 glutathione peroxidase 1 [ Homo sapiens ]
Official Symbol : GPX1
Synonyms : GPX1; glutathione peroxidase 1; GPx-1; GSHPx-1; cellular glutathione peroxidase; GPXD; GSHPX1; MGC14399; MGC88245;
Gene ID : 2876
mRNA Refseq : NM_000581
Protein Refseq : NP_000572
MIM : 138320
UniProt ID : P07203
Chromosome Location : 3p21.3
Pathway : Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Direct p53 effectors, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem;
Function : SH3 domain binding; endopeptidase inhibitor activity; glutathione peroxidase activity; glutathione peroxidase activity; oxidoreductase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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