Recombinant Human TNNI3, His-tagged
Cat.No. : | TNNI3-27665H |
Product Overview : | Recombinant Human TNNI3 was expressed as 6*his-tagged fusion protein by E.Coli and purified by Ni-sepharose. |
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Cat. No. : | TNNI3-27665H |
Description : | Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |
Source : | E. coli |
Antigen peptideregion : | 1-110aa |
Tag : | His |
Storagebuffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Storage : | The protein is stored in PBS buffer at -20 oC. Repeated freezethaw cycles should be avoided. |
OfficialSymbol : | TNNI3 |
Gene Name : | TNNI3 troponin I type 3 (cardiac) [ Homo sapiens ] |
Synonyms : | TNNI3; troponin I type 3 (cardiac); CMH7; RCM1; cTnI; CMD2A; TNNC1; MGC116817; CMD1FF; troponin I, cardiac; Troponin I, cardiac muscle; Cardiac troponin I; familial hypertrophic cardiomyopathy 7 |
Gene ID : | 7137 |
mRNA Refseq : | NM_000363 |
Protein Refseq : | NP_000354 |
MIM : | 191044 |
UniProt ID : | P19429 |
Chromosome Location : | 19q13.4 |
Pathway : | Hypertrophic cardiomyopathy (HCM); Muscle contraction; Cardiac muscle contraction |
Function : | actin binding; calcium-dependent protein binding; protein domain specific binding; protein kinase binding; troponin C binding; troponin T binding; calcium channel inhibitor activity |
Products Types
◆ Recombinant Protein | ||
Tnni3-6569M | Recombinant Mouse Tnni3 Protein, Myc/DDK-tagged | +Inquiry |
TNNI3-2254H | Recombinant Human TNNI3 Protein, MYC/DDK-tagged | +Inquiry |
Tnni3-1003H | Active Recombinant Human cTnI Protein | +Inquiry |
TNNI3-872H | Recombinant Human TNNI3 Protein, His-tagged | +Inquiry |
Tnni3-1388M | Recombinant Mouse Tert Protein, His-SUMO-tagged | +Inquiry |
◆ Native Protein | ||
TNNI3-223H | Native Human Troponin I Type 3 (Cardiac) | +Inquiry |
TNNI3-221H | Native Human TNNI3 | +Inquiry |
Tnni3-7423M | Native Mouse Tnni3 Protein | +Inquiry |
◆ Lysates | ||
TNNI3-1803HCL | Recombinant Human TNNI3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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