| Cat. No. : |
CD133-90H |
| Description : |
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Source : |
wheat germ |
| Molecular Mass : |
122.7 kDa |
| Sequence : |
MALVLGSLLLLGLCGNSFSGGQPSS TDAPKAWNYELPATNYETQDSHKAG PIGILFELVHIFLYVVQPRDFPEDT LRKFLQKAYESKIDYDKIVYYEAGI ILCCVLGLLFIILMPLVGYFFCMCR CCNKCGGEMHQRQKENGPFLRKCFA ISLLVICIIISIGIFYGFVANHQVR TRIKRSRKLADSNFKDLRTLLNETP EQIKYILAQYNTTKDKAFTDLNSIN SVLGGGILDRLRPNIIPVLDEIKSM ATAIKETKEALENMNSTLKSLHQQS TQLSSSLTSVKTSLRSSLNDPLCLV HPSSETCNSIRLSLSQLNSNPELRQ LPPVDAELDNVNNVLRTDLDGLVQQ GYQSLNDIPDRVQRQTTTVVAGIKR VLNSIGSDIDNVTQRLPIQDILSAF SVYVNNTESYIHRNLPTLEEYDSYW WLGGLVICSLLTLIVIFYYLGLLCG VCGYDRHATPTTRGCVSNTGGVFLM VGVGLSFLFCWILMIIVVLTFVFGA NVEKLICEPYTSKELFRVLDTPYLL NEDWEYYLSGKLFNKSKMKLTFEQV YSDCKKNRGTYGTLHLQNSFNISEH LNINEHTGSISSELESLKVNLNIFL LGAAGRKNLQDFAACGIDRMNYDSY LAQTGKSPAGVNLLSFAYDLEAKAN SLPPGNLRNSLKRDAQTIKTIHQQR VLPIEQSLSTLYQSVKILQRTGNGL LERVTRILASLDFAQNFITNNTSSV IIEETKKYGRTIIGYFEHYLQWIEF SISEKVASCKPVATALDTAVDVFLC SYIIDPLNLFWFGIGKATVFLLPAL IFAVKLAKYYRRMDSEDVYDDVETI PMKNMENGNNGYHKDHVYGIHNPVM TSPSQH |
| Storagebuffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer. |
| Applications : |
ELISA; WB |
| Storage : |
Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| OfficialSymbol : |
PROM1 |
