"IL9" Related Products

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Recombinant Human Interleukin 9

Cat. No.: IL9-67H
Product Overview: Recombinant Human Interleukin-9 produced inE.Coliis a single, non-glycosylated single polypeptide chain containing 127 amino acids and having a molecular mass of 14,004 Dalton. The IL-9 is purified by proprietary chromatographic techniques.
Description: Factor that is thought to be a regulator of hematopoiesis. It has been shown to enhance the growth of human mast cells and megakaryoblastic leukemic cells as well as murine helper t-cell clones. IL-9 is a glycoprotein with a molecular weight of 32-39 that is derived from T cells and maps to human chromosome 5.
Source: Escherichia Coli.
Amino Acid Sequence: The sequence of the first five N-terminal amino acids was determined and was found to be Met-Gln-Gly-Cys-Pro.
Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Purity: Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation: Lyophilized from a concentrated (1mg/ml) solution containing no additives.
Solubility: It is recommended to reconstitute the lyophilized Interleukin-9 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Biological Activity: The ED50as determined by the dose-dependant stimulation of human MO7e cells is < 0.2 ng/ml, corresponding to a Specific Activity of 5 x 106 IU/mg.
Storage: Lyophilized Interleukin-9 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL9 should be stored at 4°Cbetween 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Gene Name: IL9 interleukin 9 [ Homo sapiens ]
Synonyms: IL9; interleukin 9; P40; HP40; IL-9; p40 T-cell and mast cell growth factor; T-cell growth factor p40; p40 cytokine; homolog of mouse T cell and mast cell growth factor 40; OTTHUMP00000159423
Gene ID: 3578
mRNA Refseq: NM_000590
Protein Refseq: NP_000581
UniProt ID: P15248
Chromosome Location: 5q31.1
MIM: 146931
Pathway: Asthma; Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
Function: cytokine activity; cytokine receptor binding; growth factor activity

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