Recombinant Human AIFM2, GST-tagged

• Cat.No.: AIFM2-9504H
• Product Overview: Recombinant Human AIFM2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a flavoprotein oxidoreductase that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA. The expression of this gene is also found to be induced by tumor suppressor protein p53 in colon cancer cells.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-373a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 [ Homo sapiens ]
• Official Symbol: AIFM2
• Synonyms: AIFM2; apoptosis-inducing factor, mitochondrion-associated, 2; AMID, apoptosis inducing factor (AIF) like mitochondrion associated inducer of death; apoptosis-inducing factor 2; FLJ14497; PRG3; p53-responsive gene 3 protein; apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death; apoptosis-inducing factor (AIF)-homologous mitochondrion-associated inducer of death; AMID; RP11-367H5.2; DKFZp686L1298
• Gene ID: 84883
• mRNA Refseq: NM_032797
• Protein Refseq: NP_116186
• MIM: 605159
• UniProt ID: Q9BRQ8
• Chromosome Location: 10q22.2
• Pathway: Direct p53 effectors, organism-specific biosystem
• Function: DNA binding; electron-transferring-flavoprotein dehydrogenase activity; flavin adenine dinucleotide binding; oxidoreductase activity