Recombinant Human ALG2, His-tagged
Cat.No. : | ALG2-9575H |
Product Overview : | Recombinant Human ALG2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | C-term-292a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | ALG2 asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae) [ Homo sapiens ] |
Official Symbol : | ALG2 |
Synonyms : | ALG2; asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); asparagine linked glycosylation 2 homolog (yeast, alpha 1,3 mannosyltransferase); alpha-1,3/1,6-mannosyltransferase ALG2; CDGIi; FLJ14511; hALPG2; NET38; homolog of yeast ALG2; alpha-1,3-mannosyltransferase ALG2; asparagine-linked glycosylation protein 2 homolog; GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase; GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase); |
Gene ID : | 85365 |
mRNA Refseq : | NM_033087 |
Protein Refseq : | NP_149078 |
MIM : | 607905 |
UniProt ID : | Q9H553 |
Chromosome Location : | 9q31.1 |
Pathway : | Asparagine N-linked glycosylation, organism-specific biosystem; Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; N-Glycan biosynthesis, organism-specific biosystem; N-Glycan biosynthesis, conserved biosystem; N-glycan precursor biosynthesis, organism-specific biosystem; |
Function : | GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity; alpha-1,3-mannosyltransferase activity; calcium-dependent protein binding; calcium-dependent protein binding; protein N-terminus binding; protein anchor; protein binding; protein heterodim |
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ALG2-131R | Recombinant Rhesus Macaque ALG2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALG2-01H | Recombinant Human ALG2 Protein, Myc/DDK-tagged | +Inquiry |
ALG2-5978Z | Recombinant Zebrafish ALG2 | +Inquiry |
◆ Lysates | ||
ALG2-8906HCL | Recombinant Human ALG2 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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