Recombinant Human ARHGEF10, GST-tagged

• Cat.No.: ARHGEF10-9832H
• Product Overview: Recombinant Human ARHGEF10 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 400-700a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 [ Homo sapiens ]
• Official Symbol: ARHGEF10
• Synonyms: ARHGEF10; Rho guanine nucleotide exchange factor (GEF) 10; rho guanine nucleotide exchange factor 10; Gef10; KIAA0294; GEF10; MGC131664; DKFZp686H0726
• Gene ID: 9639
• mRNA Refseq: NM_014629
• Protein Refseq: NP_055444
• MIM: 608136
• UniProt ID: O15013
• Chromosome Location: 8p23
• Pathway: Regulation of RhoA activity, organism-specific biosystem
• Function: Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; kinesin binding