Recombinant Human ASCL2, GST-tagged

• Cat.No.: ASCL2-9926H
• Product Overview: Recombinant Human ASCL2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5-CANNTG-3). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-92a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ASCL2 achaete-scute complex homolog 2 (Drosophila) [ Homo sapiens ]
• Official Symbol: ASCL2
• Synonyms: ASCL2; achaete-scute complex homolog 2 (Drosophila); achaete scute complex (Drosophila) homolog like 2 , achaete scute complex like 2 (Drosophila); achaete-scute homolog 2; ASH2; bHLHa45; HASH2; ASH-2; achaete-scute complex-like 2; mammalian achaete/scute homologue 2; class A basic helix-loop-helix protein 45; MASH2
• Gene ID: 430
• mRNA Refseq: NM_005170
• Protein Refseq: NP_005161
• MIM: 601886
• UniProt ID: Q99929
• Chromosome Location: 11p15.5
• Function: E-box binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity