Recombinant Human ATXN3L, GST-tagged

• Cat.No.: ATXN3L-10070H
• Product Overview: Recombinant Human ATXN3L protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This intronless gene may be a pseudogene (PMID:11450850). This gene is similar to the multi-exon gene which encodes ataxin 3 and contains a coding region which could encode a protein similar to ataxin 3. Mutations in the gene encoding ataxin 3 are associated with Machado-Joseph disease.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 271-341a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ATXN3L ataxin 3-like [ Homo sapiens ]
• Official Symbol: ATXN3L
• Synonyms: ataxin 3-like; ATX3L; MJDL; EC 3.4.19.12; Machado-Joseph disease protein 1-like; EC 3.4.22; putative ataxin-3-like protein
• Gene ID: 92552
• mRNA Refseq: NM_001135995.1
• Protein Refseq: NP_001129467.1
• UniProt ID: B4DYC7
• Chromosome Location: Xp22.2
• Pathway: Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem
• Function: omega peptidase activity; ubiquitin-specific protease activity