"BAG3" Related Products

Expand
Expand
Expand

Recombinant Human BAG3, His-tagged

Cat.No.: BAG3-10125H
Product Overview: Recombinant Human BAG3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Source: E.coli
Species: Human
Tag: His
Protein length: 275-575a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: BAG3 BCL2-associated athanogene 3 [ Homo sapiens ]
Official Symbol: BAG3
Synonyms: BAG3; BCL2-associated athanogene 3; BAG family molecular chaperone regulator 3; docking protein CAIR-1; BCL2-binding athanogene 3; bcl-2-binding protein Bis; bcl-2-associated athanogene 3; BAG-family molecular chaperone regulator-3; BIS; BAG-3; CAIR-1; MGC104307;
Gene ID: 9531
mRNA Refseq: NM_004281
Protein Refseq: NP_004272
MIM: 603883
UniProt ID: O95817
Chromosome Location: 10q25.2-q26.2
Function: chaperone binding;

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.