Recombinant Human CALML5, GST-tagged

• Cat.No.: CALML5-10673H
• Product Overview: Recombinant Human CALML5 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-146a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CALML5 calmodulin-like 5 [ Homo sapiens ]
• Official Symbol: CALML5
• Synonyms: CALML5; calmodulin-like 5; calmodulin-like protein 5; calmodulin like skin protein; CLSP; calmodulin-like skin protein
• Gene ID: 51806
• mRNA Refseq: NM_017422
• Protein Refseq: NP_059118
• MIM: 605183
• UniProt ID: Q9NZT1
• Chromosome Location: 10p15.1
• Pathway: Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Dopaminergic synapse, organism-specific biosystem
• Function: calcium ion binding