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Recombinant Human CAPN2 protein, GST-tagged

Cat.No. : CAPN2-10702H
Product Overview : Recombinant Human CAPN2 protein(1-330 aa), fused with GST tag, was expressed in E.coli.
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Source : E.coli
Species : Human
Tag : GST
Form : The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 100mM GSH.
Protein Length : 1-330 aa
AA Sequence : MAGIAAKLAKDREAAEGLGSHERAI KYLNQDYEALRNECLEAGTLFQDPS FPAIPSALGFKELGPYSSKTRGIEW KRPTEICADPQFIIGGATRTDICQG ALGDCWLLAAIASLTLNEEILARVV PLNQSFQENYAGIFHFQFWQYGEWV EVVVDDRLPTKDGELLFVHSAEGSE FWSALLEKAYAKINGCYEALSGGAT TEGFEDFTGGIAEWYELKKPPPNLF KIIQKALQKGSLLGCSIDITSAADS EAITFQKLVKGHAYSVTGAEEVESN GSLQKLIRIRNPWGEVEWTGRWNDN CPSWNTIDPEERERLTRRHEDGEFW MSFSD
Purity : 85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
Storage : Short-term storage: Store at 2-8°C for (1-2 weeks).
Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
Reconstitution : Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.
Gene Name : CAPN2 calpain 2, (m/II) large subunit [ Homo sapiens ]
Official Symbol : CAPN2
Synonyms : CAPN2; calpain 2, (m/II) large subunit; calpain-2 catalytic subunit; CANPL2; CANPml; mCANP; CANP 2; M-calpain; calpain M-type; millimolar-calpain; calpain-2 large subunit; calpain 2, large subunit; calpain large polypeptide L2; calpain, large polypeptide L2; calpain 2, large [catalytic] subunit; calcium-activated neutral proteinase 2; CANP2; FLJ39928;
Gene ID : 824
mRNA Refseq : NM_001146068
Protein Refseq : NP_001139540
MIM : 114230
UniProt ID : P17655

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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How is CAPN2 protein expression regulated in normal physiological conditions? 10/15/2021

CAPN2 activity is tightly regulated by intracellular calcium levels and various other factors to maintain cellular homeostasis.

How does CAPN2 protein interact with other molecules or proteins in disease contexts? 03/10/2021

CAPN2 interacts with various cellular proteins, contributing to processes like protein degradation, cytoskeletal remodeling, and cell signaling, influencing disease pathways.

Can CAPN2 protein serve as a potential therapeutic target? 01/02/2018

Research suggests that modulating CAPN2 activity could be a potential therapeutic strategy for managing diseases associated with its dysregulation.

Are there any drugs or compounds known to modulate CAPN2 activity? 07/17/2017

Some compounds and inhibitors targeting CAPN2 have been developed in preclinical studies, showing promise in controlling its activity for therapeutic purposes.

Can CAPN2 protein levels serve as a biomarker for certain diseases? 06/07/2017

In some cases, altered levels of CAPN2 have been observed in disease states, suggesting its potential as a biomarker, but further validation is needed.

Customer Reviews (3)

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03/05/2020

    The CAPN2 protein has been extensively studied and validated in various experimental applications.

    08/03/2019

      Their team of technical experts possess deep knowledge and expertise regarding the protein, ensuring that researchers receive accurate and timely assistance.

      10/01/2017

        In addition to its advantages in trials, the manufacturer of the CAPN2 protein offers exceptional support to researchers.

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