Recombinant Human CAPN2 protein, GST-tagged
Cat.No. : | CAPN2-10702H |
Product Overview : | Recombinant Human CAPN2 protein(1-330 aa), fused with GST tag, was expressed in E.coli. |
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Source : | E.coli |
Species : | Human |
Tag : | GST |
Form : | The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 100mM GSH. |
Protein Length : | 1-330 aa |
AA Sequence : | MAGIAAKLAKDREAAEGLGSHERAI KYLNQDYEALRNECLEAGTLFQDPS FPAIPSALGFKELGPYSSKTRGIEW KRPTEICADPQFIIGGATRTDICQG ALGDCWLLAAIASLTLNEEILARVV PLNQSFQENYAGIFHFQFWQYGEWV EVVVDDRLPTKDGELLFVHSAEGSE FWSALLEKAYAKINGCYEALSGGAT TEGFEDFTGGIAEWYELKKPPPNLF KIIQKALQKGSLLGCSIDITSAADS EAITFQKLVKGHAYSVTGAEEVESN GSLQKLIRIRNPWGEVEWTGRWNDN CPSWNTIDPEERERLTRRHEDGEFW MSFSD |
Purity : | 85%, by SDS-PAGE with Coomassie Brilliant Blue staining. |
Storage : | Short-term storage: Store at 2-8°C for (1-2 weeks). Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles. |
Reconstitution : | Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage. Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage. |
Gene Name : | CAPN2 calpain 2, (m/II) large subunit [ Homo sapiens ] |
Official Symbol : | CAPN2 |
Synonyms : | CAPN2; calpain 2, (m/II) large subunit; calpain-2 catalytic subunit; CANPL2; CANPml; mCANP; CANP 2; M-calpain; calpain M-type; millimolar-calpain; calpain-2 large subunit; calpain 2, large subunit; calpain large polypeptide L2; calpain, large polypeptide L2; calpain 2, large [catalytic] subunit; calcium-activated neutral proteinase 2; CANP2; FLJ39928; |
Gene ID : | 824 |
mRNA Refseq : | NM_001146068 |
Protein Refseq : | NP_001139540 |
MIM : | 114230 |
UniProt ID : | P17655 |
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◆ Native Protein | ||
CAPN2-350B | Native Bovine CAPN2 | +Inquiry |
CAPN2-22P | Active Native Porcine CAPN2 protein | +Inquiry |
◆ Lysates | ||
CAPN2-7863HCL | Recombinant Human CAPN2 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCAPN2 activity is tightly regulated by intracellular calcium levels and various other factors to maintain cellular homeostasis.
CAPN2 interacts with various cellular proteins, contributing to processes like protein degradation, cytoskeletal remodeling, and cell signaling, influencing disease pathways.
Research suggests that modulating CAPN2 activity could be a potential therapeutic strategy for managing diseases associated with its dysregulation.
Some compounds and inhibitors targeting CAPN2 have been developed in preclinical studies, showing promise in controlling its activity for therapeutic purposes.
In some cases, altered levels of CAPN2 have been observed in disease states, suggesting its potential as a biomarker, but further validation is needed.
Customer Reviews (3)
Write a reviewThe CAPN2 protein has been extensively studied and validated in various experimental applications.
Their team of technical experts possess deep knowledge and expertise regarding the protein, ensuring that researchers receive accurate and timely assistance.
In addition to its advantages in trials, the manufacturer of the CAPN2 protein offers exceptional support to researchers.
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