Recombinant Human CASP5, GST-tagged

• Cat.No.: CASP5-10734H
• Product Overview: Recombinant Human CASP5 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-418a.a.
• Description: The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements. Two transcript variants encoding the same protein have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CASP5 caspase 5, apoptosis-related cysteine peptidase [ Homo sapiens ]
• Official Symbol: CASP5
• Synonyms: CASP5; caspase 5, apoptosis-related cysteine peptidase; caspase 5, apoptosis related cysteine protease; caspase-5; ICE(rel)III; CASP-5; TY protease; protease TY; ICE(rel)-III; protease ICH-3; caspase 5, apoptosis-related cysteine protease; ICH-3; ICEREL-III; MGC141966
• Gene ID: 838
• mRNA Refseq: NM_001136109
• Protein Refseq: NP_001129581
• MIM: 602665
• UniProt ID: P51878
• Chromosome Location: 11q22.2-q22.3
• Pathway: NOD-like receptor signaling pathway, organism-specific biosystem; NOD-like receptor signaling pathway, conserved biosystem
• Function: cysteine-type endopeptidase activity; cysteine-type peptidase activity; peptidase activity