Recombinant Human CDX2, His-tagged

• Cat.No.: CDX2-11075H
• Product Overview: Recombinant Human CDX2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-180a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CDX2 caudal type homeobox 2 [ Homo sapiens ]
• Official Symbol: CDX2
• Synonyms: CDX2; caudal type homeobox 2; caudal type homeo box transcription factor 2 , CDX3; homeobox protein CDX-2; caudal-type homeobox protein 2; caudal type homeobox transcription factor 2; caudal type homeo box transcription factor 2; CDX3; CDX-3
• Gene ID: 1045
• mRNA Refseq: NM_001265
• Protein Refseq: NP_001256
• MIM: 600297
• UniProt ID: Q99626
• Chromosome Location: 13q12.2
• Pathway: Incretin Synthesis, Secretion, and Inactivation, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Regulation of Insulin Secretion, organism-specific biosystem; Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1), organism-specific biosystem
• Function: sequence-specific DNA binding transcription factor activity; transcription corepressor activity; transcription regulatory region sequence-specific DNA binding