Recombinant Human DCTN3, GST-tagged
Cat.No. : | DCTN3-11866H |
Product Overview : | Recombinant Human DCTN3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-186a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | DCTN3 dynactin 3 (p22) [ Homo sapiens ] |
Official Symbol : | DCTN3 |
Synonyms : | DCTN3; dynactin 3 (p22); dynactin subunit 3; DCTN 22; p22; dynactin light chain; dynactin 3, isoform 1; dynactin complex subunit 22 kDa subunit; DCTN22; DCTN-22; MGC111190; |
Gene ID : | 11258 |
mRNA Refseq : | NM_007234 |
Protein Refseq : | NP_009165 |
MIM : | 607387 |
UniProt ID : | O75935 |
Chromosome Location : | 9p13 |
Pathway : | Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; G2/M Transition, organism-specific biosystem; Loss of Nlp from mitotic centrosomes, organism-specific biosystem; Loss of proteins required for interphase microtubule organization??from the centrosome, organism-specific biosystem; Mitotic G2-G2/M phases, organism-specific biosystem; |
Function : | protein binding; structural molecule activity; |
Products Types
◆ Recombinant Protein | ||
DCTN3-2413H | Recombinant Human DCTN3 Protein, GST-tagged | +Inquiry |
Dctn3-2482M | Recombinant Mouse Dctn3 Protein, Myc/DDK-tagged | +Inquiry |
DCTN3-451H | Recombinant Human DCTN3 Protein (2-176 aa), His-SUMO-tagged | +Inquiry |
DCTN3-1020R | Recombinant Rhesus Macaque DCTN3 Protein, His (Fc)-Avi-tagged | +Inquiry |
DCTN3-3093C | Recombinant Chicken DCTN3 | +Inquiry |
◆ Lysates | ||
DCTN3-7041HCL | Recombinant Human DCTN3 293 Cell Lysate | +Inquiry |
DCTN3-7040HCL | Recombinant Human DCTN3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket