Recombinant Human EGF, GST-tagged
Cat.No. : | EGF-12320H |
Product Overview : | Recombinant Human EGF protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 971-1023a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | EGF epidermal growth factor [ Homo sapiens ] |
Official Symbol : | EGF |
Synonyms : | EGF; epidermal growth factor; epidermal growth factor (beta urogastrone); pro-epidermal growth factor; beta-urogastrone; URG; HOMG4; |
Gene ID : | 1950 |
mRNA Refseq : | NM_001178130 |
Protein Refseq : | NP_001171601 |
MIM : | 131530 |
UniProt ID : | P01133 |
Chromosome Location : | 4q25 |
Pathway : | Arf6 signaling events, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Ceramide signaling pathway, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; |
Function : | calcium ion binding; epidermal growth factor receptor binding; growth factor activity; protein binding; transmembrane receptor protein tyrosine kinase activator activity; |
Products Types
◆ Native Protein | ||
Egf -634M | Active Native Mouse Egf protein | +Inquiry |
EGF-23H | Active Native Human EGF protein | +Inquiry |
Egf-634M | Active Native Mouse Egf | +Inquiry |
◆ Lysates | ||
EGF-973MCL | Recombinant Mouse EGF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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