"FBXO3" Related Products


Recombinant Human FBXO3, His-tagged

Cat.No.: FBXO3-12794H
Product Overview: Recombinant Human FBXO3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants diverging at the 3 end.
Source: E.coli
Species: Human
Tag: His
Protein length: 124-471a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: FBXO3 F-box protein 3 [ Homo sapiens ]
Official Symbol: FBXO3
Synonyms: FBXO3; F-box protein 3; F box only protein 3; F-box only protein 3; FBA; FBX3; F-box protein FBX3; DKFZp564B092;
Gene ID: 26273
mRNA Refseq: NM_012175
Protein Refseq: NP_036307
MIM: 609089
UniProt ID: Q9UK99
Chromosome Location: 11p13
Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem;
Function: ubiquitin-protein ligase activity;

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