Recombinant Human HUWE1, GST-tagged
Cat.No. : | HUWE1-14016H |
Product Overview : | Recombinant Human HUWE1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the HECT E3 ubiquitin ligase family. The HECT domain lies in the C-terminus and contains the active-site cysteine which forms an intermediate ubiquitin-thioester bond. E3 family members are divided into three subfamilies based on their protein-protein interaction domains; this gene encodes a member of the SI(ngle)-HECT E3 subfamily. In lung, breast, and colorectal carcinomas, this gene is highly expressed. Mutations in this gene has been found in 3 unrelated families with X-linked syndromic mental retardation, Turner type. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | C-term-392a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase [ Homo sapiens ] |
Official Symbol : | HUWE1 |
Synonyms : | HUWE1; HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase; HECT, UBA and WWE domain containing 1; E3 ubiquitin-protein ligase HUWE1; Ib772; KIAA0312; UREB1; ARF-binding protein 1; URE-binding protein 1; BJ-HCC-24 tumor antigen; large structure of UREB1; HECT domain protein LASU1; Mcl-1 ubiquitin ligase E3; upstream regulatory element-binding protein 1; homologous to E6AP carboxyl terminus homologous protein 9; MULE; LASU1; HECTH9; URE-B1; ARF-BP1; HSPC272; |
Gene ID : | 10075 |
mRNA Refseq : | NM_031407 |
Protein Refseq : | NP_113584 |
MIM : | 300697 |
UniProt ID : | Q7Z6Z7 |
Chromosome Location : | Xp11.22 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem; |
Function : | DNA binding; acid-amino acid ligase activity; binding; ligase activity; protein binding; ubiquitin-protein ligase activity; |
Products Types
◆ Recombinant Protein | ||
HUWE1-2000R | Recombinant Rhesus Macaque HUWE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HUWE1-136H | Recombinant Human HUWE1, GST-tagged | +Inquiry |
HUWE1-14015H | Recombinant Human HUWE1, GST-tagged | +Inquiry |
HUWE1-2179R | Recombinant Rhesus monkey HUWE1 Protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket