"IFI16" Related Products

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Recombinant Human IFI16, GST-tagged

Cat.No.: IFI16-14060H
Product Overview: Recombinant Human IFI16 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source: E.coli
Species: Human
Tag: GST
Protein length: N-term-353a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: IFI16 interferon, gamma-inducible protein 16 [ Homo sapiens ]
Official Symbol: IFI16
Synonyms: IFI16; interferon, gamma-inducible protein 16; gamma-interferon-inducible protein 16; IFNGIP1; PYHIN2; interferon-gamma induced protein IFI 16; interferon-inducible myeloid differentiation transcriptional activator; MGC9466;
Gene ID: 3428
mRNA Refseq: NM_001206567
Protein Refseq: NP_001193496
MIM: 147586
UniProt ID: Q16666
Chromosome Location: 1q22
Pathway: Id Signaling Pathway, organism-specific biosystem; Senescence and Autophagy, organism-specific biosystem;
Function: DNA binding; double-stranded DNA binding; protein binding;

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