Recombinant Human IGF2BP3, GST-tagged

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Recombinant Human IGF2BP3, GST-tagged

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Cat.No. : IGF2BP3-14103H
Product Overview : Recombinant Human IGF2BP3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5 UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
Source : E.coli
Species : Human
Tag : GST
Protein length : 240-579a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 [ Homo sapiens ]
Official Symbol : IGF2BP3
Synonyms : IGF2BP3; insulin-like growth factor 2 mRNA binding protein 3; insulin-like growth factor 2 mRNA-binding protein 3; cancer/testis antigen 98; CT98; IGF II mRNA binding protein 3; IMP 3; hKOC; VICKZ family member 3; IGF2 mRNA-binding protein 3; IGF-II mRNA-binding protein 3; KH domain containing protein overexpressed in cancer; KH domain-containing protein overexpressed in cancer; IMP3; KOC1; IMP-3; VICKZ3; DKFZp686F1078;
Gene ID : 10643
mRNA Refseq : NM_006547
Protein Refseq : NP_006538
MIM : 608259
UniProt ID : O00425
Chromosome Location : 7p15.3
Pathway : Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs), organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem;
Function : RNA binding; mRNA 3-UTR binding; mRNA 5-UTR binding; nucleotide binding; protein binding; translation regulator activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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