Recombinant Human FASLG Protein, His-tagged FASLG-151H

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Recombinant Human FASLG Protein, His-tagged

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Cat.No. :	FASLG-151H
Product Overview :	Recombinant Human Fas ligand(FASLG), transcript variant 1(NM_000639), with a His tag, was expressed in human cells.
Description :	This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.
Source :	Human Cells
Species :	Human
Tag :	His
Form :	Purified protein formulated in a sterile solution of TBS buffer, pH7.238, without any preservatives.
Molecular Mass :	31.3 kDa
Endotoxin :	Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Purity :	>90% by SDS-PAGE gel and Coomassie Blue staining
Applications :	Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.

Gene Name :	FASLG Fas ligand (TNF superfamily, member 6) [ Homo sapiens ]
Official Symbol :	FASLG
Synonyms :	FASLG; Fas ligand (TNF superfamily, member 6); APT1LG1, TNFSF6, tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand superfamily member 6; CD178; FasL; APTL; CD95 ligand; fas antigen ligand; apoptosis antigen ligand; apoptosis (APO-1) antigen ligand 1; tumor necrosis factor (ligand) superfamily, member 6; FASL; CD95L; CD95-L; TNFSF6; APT1LG1;
Gene ID :	356
mRNA Refseq :	NM_000639
Protein Refseq :	NP_000630
MIM :	134638
UniProt ID :	P48023