Active Recombinant Human HSP90AA1

• Cat.No.: HSP90AA1-70H
• Product Overview: Recombinant Human HSP90AA1 was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Form: Supplied as a solution in HEPES, KCl and TCEP.
• Bio-activity: HSP90 alpha/HSP90AA1 is a molecular chaperone that assists in the folding of nascent polypeptides and the refolding of denatured proteins. Reaction conditions will need to be optimized for each specific application.
• Molecular Mass: 85 kDa
• Purity: >85%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain.
• Storage: Avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.

Gene Information

• Gene Name: HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 [ Homo sapiens (human) ]
• Official Symbol: HSP90AA1
• Synonyms: HSP90AA1; EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock protein HSP 90-alpha; HSP 86; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kDa protein 1, alpha; renal carcinoma antigen NY-REN-38; heat shock 90kD protein, alpha-like 4; epididymis luminal secretory protein 52; heat shock 90kD protein 1, alpha-like 4
• Gene ID: 3320
• mRNA Refseq: NM_001017963
• Protein Refseq: NP_001017963
• MIM: 140571
• UniProt ID: P07900
• Chromosome Location: 14q32.33
• Pathway: AhR pathway; Antigen processing and presentation; Cell Cycle
• Function: ATP binding; ATPase activity; TPR domain binding