"FAS" Related Products

Recombinant Human FAS, Fc-tagged

Cat.No.: FAS-239H
Product Overview: The Fc portion of human IgG1 is fused to the C-terminus of human Fas (aa 26-170).
Description: FasL is a cytokine that binds to Fas/TNFRSF6, a receptor that transduces the apoptotic signal into cells. FasL is involved in cytotoxic T cell mediated apoptosis and in T cell development.
Source: HEK293 Cells
Species: Human
Tag: Fc
Form: Lyophilized. Contains PBS.
Bio-activity: Blocks the binding of FasL to Fas.
Molecular Mass: ~47kDa (SDS-PAGE)
Purity: ≥95% (SDS-PAGE)
Stability: Stable for at least 6 months after receipt when stored at -20°C.
Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions.
Concentration: 1mg/ml after reconstitution.
Gene Name: FAS Fas (TNF receptor superfamily, member 6) [ Homo sapiens ]
Official Symbol: FAS
Synonyms: FAS; Fas (TNF receptor superfamily, member 6); APT1, FAS1, TNFRSF6, tumor necrosis factor receptor superfamily, member 6; tumor necrosis factor receptor superfamily member 6; APO 1; CD95; Fas AMA; FAS 827dupA; CD95 antigen; FASLG receptor; apoptosis antigen 1; Delta Fas/APO-1/CD95; APO-1 cell surface antigen; apoptosis-mediating surface antigen FAS; tumor necrosis factor receptor superfamily, member 6; APT1; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6;
Gene ID: 355
mRNA Refseq: NM_000043
Protein Refseq: NP_000034
MIM: 134637
UniProt ID: P25445
Chromosome Location: 10q24.1
Pathway: Activation of Pro-Caspase 8, organism-specific biosystem; Adipogenesis, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Alzheimers disease, organism-specific biosystem;
Function: binding; identical protein binding; kinase binding; protein binding; receptor activity; receptor activity; signal transducer activity; transmembrane signaling receptor activity; tumor necrosis factor-activated receptor activity;

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