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Recombinant Mouse Gpx3, FLAG-tagged

Cat.No.: Gpx3-284M
Product Overview: Mouse GPX3 (aa 1-226) is fused at the C-terminus to a FLAG-tag.
Description: Glutathione peroxidase 3 (GPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma.
Source: HEK293 Cells
Species: Mouse
Tag: FLAG
Form: Liquid. 0.2μm-filtered solution in PBS, pH7.2.
Molecular Mass: ~22kDa (SDS-PAGE)
Purity: ≥90% (SDS-PAGE)
Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Gene Name: Gpx3 glutathione peroxidase 3 [ Mus musculus ]
Official Symbol: Gpx3
Synonyms: GPX3; glutathione peroxidase 3; GPx-3; GPx-P; plasma GPx; extracellular GPx; plasma glutathione peroxidase; GPx; EGPx; GSHPx-3; GSHPx-P; AA960521;
Gene ID: 14778
mRNA Refseq: NM_008161
Protein Refseq: NP_032187
Pathway: Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Folic Acid Network, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, conserved biosystem; One carbon metabolism and related pathways, organism-specific biosystem;
Function: glutathione binding; glutathione peroxidase activity; glutathione peroxidase activity; oxidoreductase activity; peroxidase activity; selenium binding;

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