Recombinant Mouse Il17a, His-tagged
Cat.No. : | Il17a-334M |
Product Overview : | Mouse IL-17A (aa 22-158) is fused at the N-terminus to a His-tag. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-17 (also known as CTLA-8) is a T cell expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpesvirus Saimiri. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. An IL-17 specific mouse cell surface receptor (IL-17R) has been cloned. While the expression of IL-17 mRNA is restricted to activated alphabetaTCR+CD4-CD8-T cells, the expression of mIL-17R mRNA has been detected in virtually all cells and tissues tested. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts; the enhancement of surface expression of ICAM-1 in fibroblasts; activation of NF-kappaB and costimulation of T cell proliferation. |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Purity : | ≥95% (SDS-PAGE) |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Storage : | Short Term Storage: +4°C; Long Term Storage: -20°C. Avoid freeze/thaw cycles. |
Gene Name : | Il17a interleukin 17A [ Mus musculus ] |
Official Symbol : | Il17a |
Synonyms : | IL17A; interleukin 17A; interleukin-17A; cytotoxic T-lymphocyte-associated antigen 8; Il17; Ctla8; IL-17; Ctla-8; IL-17A; |
Gene ID : | 16171 |
mRNA Refseq : | NM_010552 |
Protein Refseq : | NP_034682 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Rheumatoid arthritis, organism-specific biosystem; Rheumatoid arthritis, conserved biosystem; |
Function : | cytokine activity; |
Products Types
◆ Recombinant Protein | ||
IL17A-381M | Active Recombinant Mouse IL17A Protein, His-tagged | +Inquiry |
Il17a-149M | Recombinant Active Mouse IL17A Protein, His-tagged(C-ter) | +Inquiry |
IL17A-141R | Recombinant Rat IL17A Protein | +Inquiry |
IL17A-508M | Recombinant Mouse IL17A Protein | +Inquiry |
IL17A-15P | Recombinant Pig IL17A Protein (Gly26-Ser155), C-His tagged, Animal-free, Carrier-free | +Inquiry |
◆ Lysates | ||
IL17A-001HCL | Recombinant Human IL17A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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