"Tnfrsf11a" Related Products


Recombinant Mouse Tnfrsf11a, Fc-tagged

Cat.No.: Tnfrsf11a-472M
Product Overview: Mouse RANK (aa 31-214) is fused at the C-terminus to the Fc portion of human IgG1.
Description: RANK (TRANCE-R; CD265) is the receptor for RANKL/TRANCE/OPGL. It is essential for RANKL-mediated osteoclastogenesis and is involved in the regulation of interactions between T cells and dendritic cells.
Source: HEK293 Cells
Species: Mouse
Tag: Fc
Form: Lyophilized. Contains PBS.
Bio-activity: Inhibits mouse and human RANKL biological functions.
Molecular Mass: ~55kDa (SDS-PAGE)
Purity: ≥95% (SDS-PAGE)
Stability: Stable for at least 6 months after receipt when stored at -20°C.
Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions.
Concentration: 1mg/ml after reconstitution.
Gene Name: Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a [ Mus musculus ]
Official Symbol: Tnfrsf11a
Synonyms: TNFRSF11A; tumor necrosis factor receptor superfamily, member 11a; tumor necrosis factor receptor superfamily member 11A; receptor activator of NF-KB; receptor activator of NF-kappaB; osteoclast differentiation factor receptor; OFE; ODFR; Rank; Ly109; mRANK; TRANCE-R;
Gene ID: 21934
mRNA Refseq: NM_009399
Protein Refseq: NP_033425
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Osteoclast, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem; Rheumatoid arthritis, organism-specific biosystem; Rheumatoid arthritis, conserved biosystem;
Function: binding; cytokine binding; metal ion binding; protein binding; receptor activity; transmembrane signaling receptor activity; tumor necrosis factor-activated receptor activity;

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