Recombinant Mouse Tnfrsf11a, Fc-tagged

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Recombinant Mouse Tnfrsf11a, Fc-tagged

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Cat.No. : Tnfrsf11a-472M
Product Overview : Mouse RANK (aa 31-214) is fused at the C-terminus to the Fc portion of human IgG1.
Description : RANK (TRANCE-R; CD265) is the receptor for RANKL/TRANCE/OPGL. It is essential for RANKL-mediated osteoclastogenesis and is involved in the regulation of interactions between T cells and dendritic cells.
Source : HEK293 Cells
Species : Mouse
Tag : Fc
Form : Lyophilized. Contains PBS.
Bio-activity : Inhibits mouse and human RANKL biological functions.
Molecular Mass : ~55kDa (SDS-PAGE)
Purity : ≥95% (SDS-PAGE)
Stability : Stable for at least 6 months after receipt when stored at -20°C.
Storage : Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions.
Concentration : 1mg/ml after reconstitution.
Gene Name : Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a [ Mus musculus ]
Official Symbol : Tnfrsf11a
Synonyms : TNFRSF11A; tumor necrosis factor receptor superfamily, member 11a; tumor necrosis factor receptor superfamily member 11A; receptor activator of NF-KB; receptor activator of NF-kappaB; osteoclast differentiation factor receptor; OFE; ODFR; Rank; Ly109; mRANK; TRANCE-R;
Gene ID : 21934
mRNA Refseq : NM_009399
Protein Refseq : NP_033425
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Osteoclast, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem; Rheumatoid arthritis, organism-specific biosystem; Rheumatoid arthritis, conserved biosystem;
Function : binding; cytokine binding; metal ion binding; protein binding; receptor activity; transmembrane signaling receptor activity; tumor necrosis factor-activated receptor activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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