Recombinant Human AMPD3, GST-tagged

• Cat.No.: AMPD3-118H
• Product Overview: Human AMPD3 partial ORF (2 a.a. - 82 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
• Source: Wheat germ
• Species: Human
• Tag: GST
• Molecular Mass: 34.65 kDa
• AA Sequence: ALSSEPAEMPRQFPKLNISEVDEQV RLLAEKVFAKVLREEDSKDALSLFT VPEDCPIGQKEAKERELQKELAEQK SVETAK
• Applications: ELISA; WB-Re; AP; Array
• Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AMPD3 adenosine monophosphate deaminase 3 [ Homo sapiens(human) ]
• Official Symbol: AMPD3
• Synonyms: AMPD3; adenosine monophosphate deaminase 3; AMP deaminase 3; AMP aminohydrolase; myoadenylate deaminase; erythrocyte AMP deaminase; erythrocyte type AMP deaminase; erythrocyte-specific AMP deaminase; adenosine monophosphate deaminase (isoform E); EC 3.5.4.6
• Gene ID: 272
• mRNA Refseq: NM_000480
• Protein Refseq: NP_000471
• MIM: 102772
• UniProt ID: Q01432
• Chromosome Location: 11p15
• Pathway: Metabolism; Purine metabolism; Purine salvage
• Function: AMP deaminase activity; metal ion binding