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Recombinant Human IGF2BP1, MYC/DDK-tagged

Cat.No. : IGF2BP1-106H
Product Overview : Recombinant Human IGF2BP1, fused with C-terminal MYC/DDK, was expressed in HEK293 Cells.
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  • Gene Information
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Description : This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
Source : HEK293 Cells
Species : Human
Tag : MYC/DDK
Molecular Mass : 63.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 [ Homo sapiens (human) ]
Official Symbol : IGF2BP1
Synonyms : IGF2BP1; IMP1; ZBP1; CRDBP; IMP-1; CRD-BP; VICKZ1; insulin-like growth factor 2 mRNA binding protein 1; insulin-like growth factor 2 mRNA-binding protein 1; ZBP-1; VICKZ family member 1; zipcode-binding protein 1; IGF2 mRNA-binding protein 1; IGF-II mRNA-binding protein 1; coding region determinant-binding protein
Gene ID : 10642
mRNA Refseq : NM_006546
Protein Refseq : NP_006537
MIM : 608288
UniProt ID : Q9NZI8
Chromosome Location : 17q21.32
Pathway : BDNF signaling pathway; Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs); MicroRNAs in cancer
Function : mRNA 3'-UTR binding; mRNA binding; nucleotide binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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