Recombinant Human MCL1, GST-tagged
Cat.No. : | MCL1-782H |
Product Overview : | Recombinant Human MCL1 was expressed as gst-tagged fusion protein by E.Coli and purified by GSH-sepharose. |
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- Gene Information
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Description : | This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-327aa |
Storage : | The protein is stored in PBS buffer at -20 oC. Repeated freeze-thaw cycles should be avoided. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | MCL1 myeloid cell leukemia sequence 1 (BCL2-related) [ Homo sapiens (human) ] |
Official Symbol : | MCL1 |
Synonyms : | MCL1; TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; myeloid cell leukemia sequence 1 (BCL2-related); induced myeloid leukemia cell differentiation protein Mcl-1; bcl-2-like protein 3; myeloid cell leukemia ES; bcl-2-related protein EAT/mcl1 |
Gene ID : | 4170 |
mRNA Refseq : | NM_021960 |
Protein Refseq : | NP_068779 |
MIM : | 159552 |
UniProt ID : | Q07820 |
Chromosome Location : | 1q21 |
Pathway : | Apoptosis Modulation and Signaling; Direct p53 effectors; HIF-1-alpha transcription factor network |
Function : | BH3 domain binding; protein binding; protein channel activity |
Products Types
◆ Recombinant Protein | ||
Mcl1-3995M | Recombinant Mouse Mcl1 Protein, Myc/DDK-tagged | +Inquiry |
MCL1-2522R | Recombinant Rhesus Macaque MCL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
MCL1-3274R | Recombinant Rat MCL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
MCL1-1381H | Recombinant Human MCL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
MCL1-5408M | Recombinant Mouse MCL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
MCL1-4422HCL | Recombinant Human MCL1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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