Recombinant Human TSHR, MYC/DDK-tagged

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Recombinant Human TSHR, MYC/DDK-tagged

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Cat.No. : TSHR-839H
Product Overview : Recombinant Human TSHR fused with C-terminal MYC/DDK, was expressed in HEK293 Cells.
Description : The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : MYC/DDK
Molecular Mass : 28.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : TSHR thyroid stimulating hormone receptor [ Homo sapiens (human) ]
Official Symbol : TSHR
Synonyms : TSHR; LGR3; CHNG1; hTSHR-I; thyroid stimulating hormone receptor; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2
Gene ID : 7253
mRNA Refseq : NM_001142626
Protein Refseq : NP_001136098
MIM : 603372
UniProt ID : P16473
Chromosome Location : 14q31
Pathway : Arf6 signaling events; Autoimmune thyroid disease; G alpha (s) signalling events
Function : protein binding; thyroid-stimulating hormone receptor activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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