Recombinant Human TSHR, MYC/DDK-tagged TSHR-839H

Recombinant Human TSHR, MYC/DDK-tagged

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Recombinant Human TSHR, MYC/DDK-tagged

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Cat.No. : TSHR-839H
Product Overview : Recombinant Human TSHR fused with C-terminal MYC/DDK, was expressed in HEK293 Cells.
Description : The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : MYC/DDK
Molecular Mass : 28.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : TSHR thyroid stimulating hormone receptor [ Homo sapiens (human) ]
Official Symbol : TSHR
Synonyms : TSHR; LGR3; CHNG1; hTSHR-I; thyroid stimulating hormone receptor; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2
Gene ID : 7253
mRNA Refseq : NM_001142626
Protein Refseq : NP_001136098
MIM : 603372
UniProt ID : P16473
Chromosome Location : 14q31
Pathway : Arf6 signaling events; Autoimmune thyroid disease; G alpha (s) signalling events
Function : protein binding; thyroid-stimulating hormone receptor activity

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