Recombinant Human TSHR, MYC/DDK-tagged
| Cat.No. : |
TSHR-839H |
| Product Overview : |
Recombinant Human TSHR fused with C-terminal MYC/DDK, was expressed in HEK293 Cells. |
- Specification
- Gene Information
- Related Products
| Description : |
The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
MYC/DDK |
| Molecular Mass : |
28.5 kDa |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : |
>50 ug/mL as determined by microplate BCA method |
| Storage Buffer : |
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Gene Name : |
TSHR thyroid stimulating hormone receptor [ Homo sapiens (human) ] |
| Official Symbol : |
TSHR |
| Synonyms : |
TSHR; LGR3; CHNG1; hTSHR-I; thyroid stimulating hormone receptor; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2 |
| Gene ID : |
7253 |
| mRNA Refseq : |
NM_001142626 |
| Protein Refseq : |
NP_001136098 |
| MIM : |
603372 |
| UniProt ID : |
P16473 |
| Chromosome Location : |
14q31 |
| Pathway : |
Arf6 signaling events; Autoimmune thyroid disease; G alpha (s) signalling events |
| Function : |
protein binding; thyroid-stimulating hormone receptor activity |
Products Types
Related Gene
TSHR
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
