Recombinant Human AGXT, His-tagged

• Cat.No.: AGXT-84838H
• Product Overview: Recombinant Human AGXT was expressed as 6*his-tagged fusion protein by E.Coli and puri?ed by Ni-sepharose.

Specification

• Description: This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-392aa
• AA Sequence: True
• Storage: The protein is stored in PBS bu?er at -20 oC. Repeated freeze-thaw cycles should be avoided.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: AGXT alanine-glyoxylate aminotransferase [ Homo sapiens (human) ]
• Official Symbol: AGXT
• Synonyms: AGXT; AGT; PH1; SPT; AGT1; SPAT; TLH6; AGXT1; alanine-glyoxylate aminotransferase; serine--pyruvate aminotransferase; serine-pyruvate aminotransferase; serine:pyruvate aminotransferase; alanine--glyoxylate aminotransferase; L-alanine: glyoxylate aminotransferase 1; hepatic peroxisomal alanine:glyoxylate aminotransferase; NP_000021.1; EC 2.6.1.44; EC 2.6.1.51
• Gene ID: 189
• mRNA Refseq: NM_000030
• Protein Refseq: NP_000021
• MIM: 604285
• UniProt ID: P21549
• Chromosome Location: 2q37.3
• Pathway: Alanine and aspartate metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism
• Function: alanine-glyoxylate transaminase activity; protein homodimerization activity; pyridoxal phosphate binding