Recombinant Human N-6 adenine-specific DNA methyltransferase 1 (putative), His-tagged

• Cat.No.: N6AMT1-648H
• Product Overview: N6AMT1, 1-214aa Human, His tag, E.coli

Specification

• Description: N6AMT1 is a member of methyltransferase family, may be involved in the methylation of release factor I during translation termination. This protein is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternate splicing results in multiple transcript variants. Recombinant human N6ATM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid, In Phosphate buffered saline (pH7.4) containing 20% glycerol, 1mM DTT
• Molecular Mass: 25.3 kDa (237aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAGENFA TPFHGHVGRG AFSDVYEPAE DTFLLLNALE AAAAELAGVE ICLEVGSGSG VVSAFLASMI GPQALYMCTD INPEAAACTL ETARCNKVHI QPVITDLVKG LLPRLTEKVD LLVFNPPYVV TPPQEVGSHG IEAAWAGGRN GREVMDRFFP LVPDLLSPRG LFYLVTIKEN NPEEILKIMK TKGLQGTTAL SRQAGQETLS VLKFTKS
• Purity: >85 % by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative) [ Homo sapiens ]
• Official Symbol: N6AMT1
• Synonyms: N6AMT1; N-6 adenine-specific DNA methyltransferase 1 (putative); C21orf127, chromosome 21 open reading frame 127 , HemK methyltransferase family member 2 , HEMK2; hemK methyltransferase family member 2; MTQ2; N6AMT; PRED28; m.HsaHemK2P; N6-DNA-methyltransferase; n(6)-adenine-specific DNA methyltransferase 1; HEMK2; C21orf127; FLJ11616; MGC19995
• Gene ID: 29104
• mRNA Refseq: NM_013240
• Protein Refseq: NP_037372
• MIM: 614553
• UniProt ID: Q9Y5N5
• Chromosome Location: 21q21.3
• Function: nucleic acid binding; protein binding; protein methyltransferase activity; transferase activity