Recombinant Rat Cdh1, His-tagged
Cat.No. : | Cdh1-549R |
Product Overview : | A DNA sequence encoding the rat CDH1 (Q9R0T4) (Met1-Ala713) was expressed with a polyhistidine tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Source : | Human Cells |
Species : | Rat |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH7.4. |
Molecular Mass : | The recombinant rat CDH1 comprises 702 amino acids and predicts a molecular mass of 78.4 kDa. The apparent molecular mass of the recombinant protein is approximately 79 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Protein length : | Met1-Ala713 |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >85 % as determined by SDS-PAGE |
Stability : | Samples are stable for up to twelve months from date of receipt at -70℃ |
Storage : | Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | Hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | Cdh1 cadherin 1 [ Rattus norvegicus ] |
Official Symbol : | Cdh1 |
Synonyms : | CDH1; cadherin 1; cadherin-1; E-cadherin; uvomorulin; epithelial cadherin; |
Gene ID : | 83502 |
mRNA Refseq : | NM_031334 |
Protein Refseq : | NP_112624 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Adherens junctions interactions, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cell adhesionproteins, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; |
Function : | GTPase activating protein binding; GTPase activating protein binding; RPTP-like protein binding; beta-catenin binding; calcium ion binding; calcium ion binding; gamma-catenin binding; gamma-catenin binding; protein binding; protein domain specific binding |
Products Types
◆ Recombinant Protein | ||
CDH1-0969H | Recombinant Human CDH1 Protein, GST-Tagged | +Inquiry |
CDH1-946R | Recombinant Rat CDH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDH1-3118H | Recombinant Human CDH1 Protein, MYC/DDK-tagged | +Inquiry |
CDH1-2645H | Recombinant Human CDH1 protein(791-880 aa), C-His-tagged | +Inquiry |
CDH1-208H | Recombinant Human CDH1 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
CDH1-736RCL | Recombinant Rat CDH1 cell lysate | +Inquiry |
CDH1-1892MCL | Recombinant Mouse CDH1 cell lysate | +Inquiry |
CDH1-938HCL | Recombinant Human CDH1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionCDH1 gene mutations are usually passed on in an autosomal dominant manner, depending on the type and location of the mutation.
Carriers of CDH1 gene mutations should have gastroscopy, ultrasonography, and other related tests to monitor the development and progression of stomach cancer.
For people with mutations in the CDH1 gene, prophylactic total gastrectomy may reduce the risk of diffuse stomach cancer. There is currently no specific treatment to target CDH1 gene mutations.
CDH1 gene mutation is closely related to the occurrence of diffuse gastric cancer, which is a special subtype of gastric cancer with a high degree of invasion and malignancy.
The CDH1 gene encodes a protein called E-calcin that plays an important role in cell adhesion and tissue differentiation. Mutations in the CDH1 gene may affect these processes, resulting in abnormal cell adhesion and tissue differentiation.
CDH1 gene mutations may be associated with the development of a small number of breast cancers, because CDH1 also plays a role in regulating cell adhesion and tissue structure in breast tissue.
Customer Reviews (3)
Write a reviewThis recombinant protein has a very short half-life and shows a very high clearance rate, which makes its biological activity more stable.
The protein was highly purified and was not doped with other proteins or impurities.
CDH1 has similar activity to the native protein and is able to perform the expected biological functions.
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