Recombinant Human PFKFB2, GST-tagged
Cat.No. : | PFKFB2-67H |
Product Overview : | Recombinant full-length human PFKFB2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | PFKFB2 is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. PFKFB2 has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFKFB2 regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. PFKFB2 also functions as a homodimer. PFKFB2 play an important role in the regulation of muscle glycolysis during the first moments of exercise. |
Source : | Sf9 insect cells using baculovirus |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~84 kDa |
Applications : | Western Blot |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 [ Homo sapiens ] |
Official Symbol : | PFKFB2 |
Synonyms : | PFK-2/FBPase-2 |
Gene ID : | 5208 |
mRNA Refseq : | NM_006212.2 |
Protein Refseq : | NP_006203.2 |
MIM : | 171835 |
UniProt ID : | O60825 |
Chromosome Location : | 1q31 |
Pathway : | Fructose and mannose metabolism, organism-specific biosystem;Fructose and mannose metabolism, conserved biosystem;Glucose metabolism, organism-specific biosystem;Glycolysis, organism-specific biosystem;Metabolism, organism-specific biosystem;Metabolism of carbohydrates, organism-specific biosystem; |
Function : | 6-phosphofructo-2-kinase activity;ATP binding;fructose-2,6-bisphosphate 2-phosphatase activity;protein binding;protein kinase binding; |
Products Types
◆ Recombinant Protein | ||
PFKFB2-4051R | Recombinant Rat PFKFB2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PFKFB2-3202R | Recombinant Rhesus Macaque PFKFB2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PFKFB2-3384R | Recombinant Rhesus monkey PFKFB2 Protein, His-tagged | +Inquiry |
PFKFB2-4009H | Recombinant Human PFKFB2 protein, His-tagged | +Inquiry |
PFKFB2-4391R | Recombinant Rat PFKFB2 Protein | +Inquiry |
◆ Lysates | ||
PFKFB2-3275HCL | Recombinant Human PFKFB2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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