Recombinant Rat Ass1, His-tagged

• Cat.No.: Ass1-3630R
• Product Overview: Argininosuccinate synthase (Ass1)

Specification

• Description: catalyzes the conversion of ATP, L-citrulline, and L-aspartate to AMP, diphosphate, and L-argininosuccinate in arginine biosynthesis; may regulate nitric oxide production .
• Source: E. Coli or Yeast
• Species: Rat
• Tag: His
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Protein length: 412
• Purity: >90%
• Notes: Small volumes of Ass1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: Ass1 argininosuccinate synthase 1 [ Rattus norvegicus ]
• Official Symbol: Ass1
• Synonyms: ASS1; argininosuccinate synthase 1; argininosuccinate synthase; arginosuccinate synthetase 1; citrulline--aspartate ligase; argininosuccinate synthetase 1; Ass; ASSA
• Gene ID: 25698
• mRNA Refseq: NM_013157
• Protein Refseq: NP_037289
• Pathway: Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem
• Function: ATP binding; argininosuccinate synthase activity; argininosuccinate synthase activity; ligase activity; nucleotide binding; toxin binding

Reviews

09/04/2020

Critical expertise in protein engineering, a trusted research resource.

10/01/2019

Dependable peptide synthesis, accelerates our peptide-based projects effectively.

08/10/2018

Efficient protein purification, cost-effective and dependable.

Q&As

What are the mechanisms by which ASS1 modulates cell growth and proliferation?

ASS1 regulates cell growth by controlling the availability of arginine, a key amino acid for cell proliferation.

How does ASS1 deficiency contribute to the development of urea cycle disorders and hyperammonemia?

ASS1 deficiency leads to urea cycle disorders, causing hyperammonemia and metabolic imbalances.

What is the impact of ASS1 on amino acid metabolism and overall cellular function?

ASS1 affects amino acid metabolism, playing a critical role in cellular health and function.

How does ASS1 (Argininosuccinate Synthase 1) function in the urea cycle and nitrogen metabolism?

ASS1 is essential in the urea cycle, converting nitrogen waste into urea for excretion and maintaining nitrogen balance.

How do alterations in ASS1 expression or activity affect cardiovascular health and disease?

Variations in ASS1 activity can impact cardiovascular health, influencing nitric oxide production and vascular function.

What role does ASS1 play in the synthesis of arginine and its impact on nitric oxide production?

ASS1 is involved in arginine synthesis, impacting nitric oxide levels and vascular function.

How does ASS1 influence the response to high-protein diets or dietary restrictions in metabolic health?

ASS1 influences how the body metabolizes high-protein diets, affecting metabolic responses and health.