Active Recombinant Bovine GM-CSF

• Cat.No.: CSF2-79B
• Product Overview: Bovine GM-CSF was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.

Specification

• Description: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a protein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. Granulocyte macrophage–colony stimulating factor (GM-CSF) is secreted in response to inflammatory stimuli such as LPS, IL-1, and TNF-α by a variety of different cells, including endothelium, fibroblasts, muscle cells, and macrophages, and by activated T cells. GM-CSF is glycosylated in its mature form.
• Source: Yeast
• Species: Bovine
• Form: Lyophilized
• Bio-activity: The biological activity of recombinant bovine GM-CSF was measured in a cell proliferation assay using the human TF-1 cell line. The ED50 for this effect is typically 2.5 - 4.0 ng/mL.
• Molecular Mass: 14.3 kDa
• AA Sequence: APTRPPNTAT RPWQHVDAIK EALSLLNHSS DTDAVMNDTE VVSEKFDSQE PTCLQTRLKL YKNGLQGSLT SLMGSLTMMA THYEKHCPPT PETSCGTQFI SFKNFKEDLK EFLFIIPFDC WEPAQK (126)
• Applications: The GM-CSF protein can be used in cell culture, as a GM-CSF ELISA Standard, and as a Western Blot Control.
• Storage: -20 C