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Recombinant Swine Il10

Cat.No. : Il10-17S
Product Overview : Swine IL-10 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
  • Specification
  • Gene Information
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Description : The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28A, IL-28B, and IL-29. These cytokines elicit diverse host defense mechanisms. IL-10 family cytokines are essential for maintaining the integrity and homeostasis of tissue epithelial layers. By promoting inamte immune response, members of this family can limit the damage caused by viral and bacterial infections. They can also facilitate the tissue-healing process in injuries caused by infection or inflammation. IL-10 itself is an anti-inflammatory cytokine. IL-10 family cytokines have indispensable functions in many infectious and inflammatory diseases. Across 12 species (Bovine IL-10, Canine IL-10, Chicken IL-10, Equine IL-10, Feline IL-10, Guinea Pig IL-10, Human IL-10, Mouse IL-10, Ovine IL-10, Rabbit IL-10, Swine IL-10, and Turkey IL-10), IL-10 homology varies greatly.
Source : Yeast
Species : Swine
Form : Lyophilized
Molecular Mass : Swine IL-10 has a predicted molecular weight of 18.1 kDa.
AA Sequence : SIKSENSCIH FPTSLPHMLR ELRAAFGPVK SFFQTKDQMG DLLLTGSLLE DFKGYLGCQA LSEMIQFYLE DVMPKAESDG EDIKEHVNSL GEKLKTLRLR LRRCHQFLPC ENKSKAVEEV KSAFSKLQER GVYKAMGEFD IFINYIEAYM TMKMRKN (157)
Purity : >95% as visualized by SDS-PAGE analysis.
Applications : The swine IL-10 protein can be used in cell culture, as a IL-10 ELISA Standard, and as a Western Blot Control.
Storage : Stable for up to twelve months from date of receipt at -20 oC. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20 oC. Avoid repeated freeze/thaw cycles.
Reconstitution : Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Gene Name : IL10 interleukin 10 [ Sus scrofa (pig) ]
Official Symbol : IL10
Synonyms : IL10; CSIF; IL-10; interleukin-10; cytokine synthesis inhibitory factor
Gene ID : 397106
mRNA Refseq : NM_214041
Protein Refseq : NP_999206
UniProt ID : Q29055
Chromosome Location : 9
Pathway : African trypanosomiasis; Autoimmune thyroid disease; Chagas disease (American trypanosomiasis)

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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