| Description : |
Tumor necrosis factor alpha (TNFSF2) is a member of the TNF Superfamily. It is produced chiefly by activated macrophages, but it is produced also by a broad variety of cell types including lymphoid cells, mast cells, endothelial cells, cardiac myocytes, adipose tissue, fibroblasts, and neuronal tissue. The primary role of TNF alpha is in the regulation of immune cells. TNF alpha, being an endogenous pyrogen, is able to induce fever, to induce apoptotic cell death, to induce sepsis (through IL-1 & IL-6 production), to induce cachexia, induce inflammation, and to inhibit tumorigenesis and viral replication. |
| Source : |
Yeast |
| Species : |
Guinea Pig |
| Form : |
Lyophilized. |
| Bio-activity : |
In testing |
| Molecular Mass : |
Guinea Pig TNF alpha has a predicted molecular weight of 17.0 kDa. |
| AA Sequence : |
SASQNDNDKP VAHVVANQQA EEELQWLSKR ANALLANGMG LSDNQLVVPS DGLYLIYSQV LFKGQGCPSY LLLTHTVSRL AVSYPEKVNL LSAIKSPCQK ETPEGAERKP WYEPIYLGGV FQLQKGDRLS AEVNLPQYLD FADSGQIYFG VIAL (154) |
| Purity : |
>95% as visualized by SDS-PAGE analysis. |
| Applications : |
The Guinea Pig TNF alpha protein can be used in cell culture, as an TNF alpha ELISA Standard, and as a Western Blot Control. |
| Storage : |
Stable for up to twelve months from date of receipt at -20?C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20?C. Avoid repeated freeze/thaw cycles. |
| Reconstitution : |
Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
