Recombinant Human FLNA, GST-tagged
Cat.No. : | FLNA-289H |
Product Overview : | Recombinant Human FLNA(1 a.a. - 838 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 117.92 kDa |
AA Sequence : | MPSGKVAQPTITDNKDGTVTVRYAP SEAGLHEMDIRYDNMHIPGSPLQFY VDYVNCGHVTAYGPGLTHGVVNKPA TFTVNTKDAGEGGLSLAIEGPSKAE ISCTDNQDGTCSVSYLPVLPGDYSI LVKYNEQHVPGSPFTARVTGDDSMR MSHLKVGSAADIPINISETDLSLLT ATVVPPSGREEPCLLKRLRNGHVGI SFVPKETGEHLVHVKKNGQHVASSP IPVVISQSEIGDASRVRVSGQGLHE GHTFEPAEFIIDTRDAGYGGLSLSI EGPSKVDINTEDLEDGTCRVTYCPT EPGNYIINIKFADQHVPGSPFSVKV TGEGRVKESITRRRRAPSVANVGSH CDLSLKIPEISIQDMTAQVTSPSGK THEAEIVEGENHTYCIRFVPAEMGT HTVSVKYKGQHVPGSPFQFTVGPLG EGGAHKVRAGGPGLERAEAGVPAEF SIWTREAGAGGLAIAVEGPSKAEIS FEDRKDGSCGVAYVVQEPGDYEVSV KFNEEHIPDSPFVVPVASPSGDARR LTVSSLQESGLKVNQPASFAVSLNG AKGAIDAKVHSPSGALEECYVTEID QDKYAVRFIPRENGVYLIDVKFNGT HIPGSPFKIRVGEPGHGGDPGLVSA YGAGLEGGVTGNPAEFVVNTSNAGA GALSVTIDGPSKVKMDCQECPEGYR VTYTPMAPGSYLISIKYGGPYHIGG SPFKAKVTGPRLVSNHSLHETSSVF VDSLTKATCAPQHGAPGPGPADASK VVAKGLGLSKAYVGQKSSFTVDCSK AGNNMLLVGVHGPRTPCEEILVKHV GSRLYSVSYLLKDKGEYTLVVKWGD EHIPGSPYRVVVP |
Applications : | ELISA; WB-Re; AP; Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | FLNA filamin A, alpha [ Homo sapiens ] |
Official Symbol : | FLNA |
Synonyms : | FLNA; filamin A, alpha; FLN; FMD; MNS; OPD; ABPX; CSBS; CVD1; FLN1; NHBP; OPD1; OPD2; XLVD; XMVD; FLN-A; ABP-280; filamin-A; filamin-1; alpha-filamin; non-muscle filamin; actin binding protein 280; endothelial actin-binding protein |
Gene ID : | 2316 |
mRNA Refseq : | NM_001456 |
Protein Refseq : | NP_001447 |
MIM : | 300017 |
UniProt ID : | P21333 |
Chromosome Location : | Xq28 |
Pathway : | Androgen receptor signaling pathway; Cell junction organization; Cell-Cell communication |
Function : | Fc-gamma receptor I complex binding; Rac GTPase binding; Ral GTPase binding |
Products Types
◆ Recombinant Protein | ||
FLNA-413H | Recombinant Human FLNA Protein, His-tagged | +Inquiry |
Flna-3038M | Recombinant Mouse Flna Protein, Myc/DDK-tagged | +Inquiry |
FLNA-185H | Recombinant Human FLNA protein, MYC/DDK-tagged | +Inquiry |
FLNA-6143C | Recombinant Chicken FLNA | +Inquiry |
FLNA-28906TH | Recombinant Human FLNA, His-tagged | +Inquiry |
◆ Native Protein | ||
FLNA-170C | Active Native chicken FLNA | +Inquiry |
FLNA-873T | Native Turkey FLNA Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket