Native Human Factor D


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Native Human Factor D

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Cat.No. : CFD-348H
Product Overview : Native Human Factor D was purified from human serum.
Description : The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.
Source : Human serum
Species : Human
Form : Frozen liquid
Bio-activity : >95% versus normal human serum standard
Molecular Mass : 24,000 Da (single chain)
Purity : ≥95% by SDS-PAGE
Characteristic : Molecular weight: 24,000 daltons.
Storage : -70°°C or below. Avoid freeze/thaw.
Storage Buffer : 10 mM sodium phosphate, 145 mM NaCl, pH 7.3
Preservative : None, 0.22 μm filtered
Warning : Use normal precautions for handling human blood products.
Gene Name : CFD complement factor D (adipsin) [ Homo sapiens ]
Official Symbol : CFD
Synonyms : CFD; complement factor D (adipsin); D component of complement (adipsin) , DF, PFD, properdin factor D; complement factor D; ADN; properdin factor D; C3 convertase activator; complement factor D preproprotein; D component of complement (adipsin); DF; PFD;
Gene ID : 1675
mRNA Refseq : NM_001928
Protein Refseq : NP_001919
MIM : 134350
UniProt ID : P00746
Chromosome Location : 19p13.3
Pathway : Adipogenesis, organism-specific biosystem; Alternative complement activation, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Hemostasis, organism-specific biosystem; Immune System, organism-specific biosystem;
Function : peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity;

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