Active Native Human Factor D

• Cat.No.: CFD-348H
• Product Overview: Native Human Factor D was purified from human serum.

Specification

• Description: The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.
• Source: Human serum
• Species: Human
• Form: Frozen liquid
• Bio-activity: >95% versus normal human serum standard
• Molecular Mass: 24,000 Da (single chain)
• Purity: ≥95% by SDS-PAGE
• Characteristic: Molecular weight: 24,000 daltons.
• Storage: -70°°C or below. Avoid freeze/thaw.
• Storage Buffer: 10 mM sodium phosphate, 145 mM NaCl, pH 7.3
• Preservative: None, 0.22 μm filtered
• Warning: Use normal precautions for handling human blood products.

Gene Information

• Gene Name: CFD complement factor D (adipsin) [ Homo sapiens ]
• Official Symbol: CFD
• Synonyms: CFD; complement factor D (adipsin); D component of complement (adipsin) , DF, PFD, properdin factor D; complement factor D; ADN; properdin factor D; C3 convertase activator; complement factor D preproprotein; D component of complement (adipsin); DF; PFD
• Gene ID: 1675
• mRNA Refseq: NM_001928
• Protein Refseq: NP_001919
• MIM: 134350
• UniProt ID: P00746
• Chromosome Location: 19p13.3
• Pathway: Adipogenesis, organism-specific biosystem; Alternative complement activation, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Hemostasis, organism-specific biosystem; Immune System, organism-specific biosystem
• Function: peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity