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Native Human Factor D

Cat.No.: CFD-348H
Product Overview: Native Human Factor D was purified from human serum.
Description: The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.
Source: Human serum
Species: Human
Form: Frozen liquid
Bio-activity: >95% versus normal human serum standard
Molecular Mass: 24,000 Da (single chain)
Purity: ≥95% by SDS-PAGE
Characteristic: Molecular weight: 24,000 daltons.
Storage: -70°°C or below. Avoid freeze/thaw.
Storage Buffer: 10 mM sodium phosphate, 145 mM NaCl, pH 7.3
Preservative: None, 0.22 μm filtered
Warning: Use normal precautions for handling human blood products.
Gene Name: CFD complement factor D (adipsin) [ Homo sapiens ]
Official Symbol: CFD
Synonyms: CFD; complement factor D (adipsin); D component of complement (adipsin) , DF, PFD, properdin factor D; complement factor D; ADN; properdin factor D; C3 convertase activator; complement factor D preproprotein; D component of complement (adipsin); DF; PFD;
Gene ID: 1675
mRNA Refseq: NM_001928
Protein Refseq: NP_001919
MIM: 134350
UniProt ID: P00746
Chromosome Location: 19p13.3
Pathway: Adipogenesis, organism-specific biosystem; Alternative complement activation, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Hemostasis, organism-specific biosystem; Immune System, organism-specific biosystem;
Function: peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity;

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